Moving from the study of muscle cells to the serve cells that control them, Dr. Miller's lab is focused on understanding the formation of synapses. They showed that the C. elegans UNC-4 and UNC-37 genes control downstream genes that generate synapses and created a cell culture system they use to compare gene expression of purified wild-type vs. mutant neurons. Current studies are at the genone / transcriptome level. [More...]
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